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Tanning / sexual

Melanotan II

Also known as MT-2

Deep tan plus a libido kick from one melanocortin peptide.

Early / anecdotal

Overview

Melanotan II (MT-2) is a synthetic melanocortin peptide that stimulates melanin production in the skin to produce a deep tan - and, as a secondary effect, also activates melanocortin receptors linked to libido. It is one of the more potent tanning compounds available in the peptide space. How it works: MT-2 is a broad melanocortin agonist. Melanin is the pigment that darkens skin in response to UV exposure, and MT-2 tells the body to produce more of it, deepening the tan with less sun exposure required. The same melanocortin pathways also influence libido, which is why sexual drive is a secondary effect at weight 2. Who tends to use it: MT-2 is used by people whose primary goal is a deeper or more lasting skin tan, with some also seeking the libido benefit as a secondary outcome. It pairs with PT-141 in some protocols for combined tanning and sexual health goals. What to expect: Tanning results typically require a loading phase before transitioning to a maintenance dose. The depth of tan and the libido effect are both dose-dependent. Spontaneous erections are a known side effect in men at higher doses. How it is taken: MT-2 is given by subcutaneous injection. The starting dose is 250 mcg, with titration upward based on response. It is taken in the evening during loading, then maintained at a lower frequency once the target tan is achieved. Cycle length extends until the desired tan is reached, then shifts to maintenance. Safety notes: MT-2 darkens existing moles, which requires a baseline mole check before starting. Nausea is common, particularly at the start. Spontaneous erections occur in some men. MT-2 is excluded for people with a history of cancer and during pregnancy. It is not FDA-approved and is classified as a research compound. Evidence level is anecdotal. Your starting dose, titration schedule, and safety screening are set at a PepDepo consultation.

At a glance

Route
SC injection
Dose
Start 250 mcg, titrate
Frequency
Loading then maintenance
Timing
Evening
Cycle
Until desired tan, then maintain

Combining

Stacks well with: PT-141

Safety

Darkens moles, nausea, can cause spontaneous erections; check moles first.

Regulatory: Not approved; research compound.

Not appropriate if: cancer-history, pregnant.

Questions

What does Melanotan II actually do?

It stimulates your body to produce more melanin - the pigment responsible for skin tanning - while also activating melanocortin receptors that drive libido. It produces a deeper tan and, as a secondary effect, increased sex drive.

How is MT-2 taken?

By subcutaneous injection, starting at 250 mcg and titrated upward based on response. It is taken in the evening during the loading phase. Once the target tan is achieved, dosing shifts to a maintenance frequency.

What are the main safety concerns with MT-2?

MT-2 darkens existing moles, so a baseline mole check is required before starting. Nausea is common especially early in the protocol. Spontaneous erections are a known side effect in men. It is excluded for anyone with a cancer history or during pregnancy.

Who should not use MT-2?

People with a personal cancer history or who are pregnant should not use MT-2. The cancer-history exclusion is firm.

Is Melanotan II FDA-approved?

No. It is a research compound and not FDA-approved.

What is the evidence quality for MT-2?

Anecdotal. The evidence base is not at the clinical trial level.

Can MT-2 be combined with PT-141?

Yes, PT-141 is listed as a synergistic companion for protocols targeting both tanning and libido.

Want a personalized protocol?

Exact dosing is set with a licensed provider in the PepDepo network. This page is education, not a prescription.

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Education only, not medical advice. Peptides discussed are for informational purposes and many are not FDA-approved. Eligibility, prescribing, compounding, and dispensing are handled by appropriately licensed entities. Exact protocols and dosing are set with a licensed provider in the PepDepo network at consult. Content is pending clinical review.