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Nootropic / anxiolytic

Selank

Calm focus without sedation, the anti-anxiety partner to Semax.

Emerging evidence

Overview

Selank is a synthetic analog of tuftsin, a natural immune-active tetrapeptide. Like Semax, it was developed in Russia, where it has been approved as a prescription medication. In the US it is a research compound. How it works: Selank balances GABA and serotonin activity in the brain. The practical effect is a reduction in anxiety and stress without sedation - you stay alert and sharp while the background noise of worry quiets down. Who tends to use it: People whose main goal is mood and stress resilience, particularly those who find that anxiety is their biggest barrier to clear thinking. Selank also carries a secondary rating for cognition, so it is often paired with Semax when someone wants both calm and focus. How it is taken: Selank is administered intranasally. The general range is 300-900 mcg, dosed once or twice daily. Unlike Semax, timing is flexible - it can be used at any time of day because it does not have the stimulating quality that makes late dosing an issue. Cycles run 2-4 weeks with a break afterward. What to expect: The primary experience is reduced anxiety with preserved mental clarity. It is explicitly non-sedating, which sets it apart from most anxiolytic medications. Safety: Selank is well tolerated. There are no excludeIf flags in the record - no contraindications for pregnancy or cancer history are listed for this peptide. That said, as a research compound in the US, a clinical consult is always appropriate before starting. Your licensed provider in the PepDepo network will determine the right dose and timing at consult based on your full health profile.

At a glance

Route
Intranasal
Dose
300-900 mcg
Frequency
1-2x daily
Timing
Any time
Cycle
2-4 weeks on, break

Combining

Stacks well with: Semax

Safety

Well tolerated; non-sedating.

Regulatory: Approved in Russia; research compound in the US.

Questions

How is Selank taken?

Intranasally - drops applied inside the nostrils. The general range is 300-900 mcg per dose, given once or twice daily.

Will it make me drowsy?

No. The record specifically notes it is non-sedating. It reduces anxiety while keeping you alert, which is what distinguishes it from sedative anxiolytics.

Can I take it at any time of day?

Yes. Unlike Semax, Selank does not have a stimulating quality, so timing is flexible. You can use it morning, afternoon, or evening.

What goals is Selank primarily used for?

Mood and stress resilience is its primary rating. Cognition is a strong secondary. It is not listed for physical goals like recovery or fat loss.

Are there any contraindications?

The record lists no excludeIf flags - no current contraindications for pregnancy or cancer history. It is described as well tolerated. Your clinician will review your full history at consult.

Does it stack well with other peptides?

Selank and Semax are the natural pairing - Semax for focus and mental drive, Selank for calm. Many people use them together during the same cycle.

How long is a typical cycle?

2-4 weeks on, then a break. Cycling is standard practice with this class of peptide.

Related protocols

Want a personalized protocol?

Exact dosing is set with a licensed provider in the PepDepo network. This page is education, not a prescription.

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Education only, not medical advice. Peptides discussed are for informational purposes and many are not FDA-approved. Eligibility, prescribing, compounding, and dispensing are handled by appropriately licensed entities. Exact protocols and dosing are set with a licensed provider in the PepDepo network at consult. Content is pending clinical review.