Protocol · Heal & recover

Repair

The classic joint, tendon, and soft-tissue healing duo.

In this protocol

Overview

Repair is the classic peptide protocol for joint, tendon, and soft-tissue healing. It uses two peptides with a long track record of being used together: BPC-157 and TB-500. BPC-157 - Body Protection Compound - is a gastric-derived peptide known for accelerating tissue repair and promoting new blood vessel formation. It has a strong reputation in the healing peptide space for joint and tendon injuries, and also has documented effects on gut inflammation. It works locally, which is why it's often injected near the site of the injury when possible. TB-500 is a fragment of Thymosin Beta-4 that works systemically - meaning throughout the body rather than at one site. It promotes cell migration, the formation of new blood vessels, and tissue repair more broadly. It's also associated with improvements in flexibility, which matters for connective-tissue recovery. Where BPC-157 digs into a specific injury site, TB-500 supports the systemic environment for healing. Together, the two peptides cover local and systemic repair at the same time. This is why they've become the standard pairing for healing protocols - neither alone covers as much ground as the two together. The schedule reflects their different action profiles. BPC-157 is dosed once or twice daily for consistent local signaling. TB-500 is dosed once or twice weekly - its systemic effect doesn't require daily dosing. A typical Repair course runs 4 to 8 weeks. People using this stack for an active injury generally notice a reduction in pain and stiffness over the first few weeks, with continued tissue rebuilding through the full course. Exact dosing, injection technique, and cycle length are set with a licensed provider in the PepDepo network at your consult.

How it runs

BPC-157 once or twice daily, TB-500 once or twice weekly for 4-8 weeks.

BPC-157 drives local tissue repair while TB-500 works systemically on flexibility and new blood vessels.

Questions

What is this stack designed for?⌄

Repair is built for joint, tendon, and soft-tissue injuries - the kind of damage that's slow to heal on its own. It's also the foundation other healing stacks build on. It's not designed for general wellness or body composition.

How is this stack run?⌄

BPC-157 is injected subcutaneously once or twice daily, ideally near the injury site when possible. TB-500 is injected subcutaneously once or twice per week. The course typically runs 4 to 8 weeks.

Why two peptides instead of just BPC-157?⌄

BPC-157 acts locally and is strong for direct tissue repair and gut healing. TB-500 works systemically - across the whole body - and supports cell migration, flexibility, and new blood vessel formation. The combination covers both local and systemic healing simultaneously.

How long before I notice a difference?⌄

Most people report reduced pain and stiffness in the first few weeks, with continued improvement through the full 4 to 8 week course. Healing timelines vary depending on the injury, its severity, and individual factors your clinician will consider.

Can I use this stack for gut issues?⌄

BPC-157 has documented anti-inflammatory effects in the gut and is used in gut-healing protocols. However, the Repair stack is specifically configured for joint and soft-tissue healing. If gut health is your primary goal, discuss that focus at your consult.

Are there safety concerns I should know about?⌄

BPC-157 is on the FDA's restricted bulk-substance list, so availability varies by pharmacy. TB-500 carries a theoretical caution for people with active cancer. Both are excluded for people with a cancer history. Your health intake covers these before the protocol is started.

Does this stack require an injection near my injury?⌄

BPC-157 is described as dosed 'near the injury site when possible.' Proximity helps concentrate the local repair signal, but your clinician will guide you on injection technique based on the location and nature of your injury.

Run this protocol safely

A licensed provider in the PepDepo network sets your exact protocol and dosing.

Book a consult

Education only, not medical advice. Peptides discussed are for informational purposes and many are not FDA-approved. Eligibility, prescribing, compounding, and dispensing are handled by appropriately licensed entities. Exact protocols and dosing are set with a licensed provider in the PepDepo network at consult. Content is pending clinical review.