AOD-9604

AOD-9604, also known as GH fragment 176-191, is a modified fragment of the growth hormone molecule - specifically the portion of GH that relates to fat metabolism. Researchers isolated this region and synthesized it as a standalone peptide to capture the fat-burning signal of GH without the other effects that come with full growth hormone, such as blood sugar changes or IGF-1 elevation. Its mechanism is direct: it stimulates fat breakdown without affecting insulin or blood sugar. This makes it distinct from the GH secretagogues, which raise GH overall and affect a broader range of systems. AOD-9604's tight focus on fat metabolism is its defining feature. Fat loss is its primary goal, with recovery as a secondary benefit. It tends to be considered for people focused specifically on body composition who want a fat-targeted tool without the systemic GH effects. AOD-9604 is given as a subcutaneous injection at 300 mcg, once daily in the morning on an empty stomach. Courses typically run eight to twelve weeks. The morning timing and empty stomach are consistent with targeting fat metabolism during a fasted state. Tolerance is very good - it is one of the better-tolerated peptides in the catalog and has no cancer-history contraindication, which is notable compared to the GH secretagogues. There are no compounds it should specifically be avoided with, and it pairs well with tesamorelin and semaglutide for a more comprehensive fat-loss approach. In the US, AOD-9604 is available as a research or compounded preparation with an emerging evidence base. Your licensed provider in the PepDepo network will set the exact protocol and determine whether it fits your goals at consult.